Eseye Feleke on Muck Rack

Eseye Feleke

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Articles

Epigenetic adaptation of beta cells across lifespan and disease

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By Elisabetta Manduchi, Hélène Descamps, Jinping Liu, Jonathan Schug, Deeksha Lahori, Hilana El-Mekkoussi, Michelle Lee, Diana Bernstein, Chengyang Liu, Ali Naji, Benjamin Glaser, Klaus H. Kaestner, Dana Avrahami, Eseye Feleke
| Nature Verified
Abstract Although the prevalence of type 2 diabetes (T2D) increases with age, most adults maintain normoglycaemia despite rising insulin resistance owing to the adaptive capacity of pancreatic beta cells to meet increased metabolic demand. However, persistent insulin resistance can lead to beta cell dysfunction and T2D onset.
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