Ettehad Marvasti

Introduction Investigating gut microbiota has emerged as a novel approach to exploring the gut-muscle axis and its link to age-related conditions like sarcopenia. While studies suggest gut dysbiosis may promote inflammation and muscle loss, findings vary by region and ethnicity. This study examined the association between gut microbiota and primary sarcopenia in an older adult population in Iran.

Abstract Metabolic syndrome (MetS) is a significant health concern in older adults, increasing the risk of chronic diseases such as cardiovascular disease and type 2 diabetes. The high prevalence of MetS, particularly among aging populations, highlights the need to understand its underlying mechanisms. Previous studies have shown that gut microbiota dysbiosis is associated with MetS. The aim of this study is to compare gut microbiota composition between older adults with and without MetS.

1. Introduction Polycystic ovarian syndrome (PCOS) is the most common endocrine disease in women of reproductive age, with an estimated prevalence of 6–26% worldwide. Increased awareness and screening have led to increasing diagnoses of this disease in adolescents. Although insulin resistance, impaired gonadotropin signaling, and altered ovarian reactivity have all been suggested for pathogenesis, the primary underlying cause of PCOS remains unknown (1).