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Eugenio Barone on Muck Rack

Eugenio Barone

As seen in: Frontiers, MDPI, Science Magazine, El Debate (Spain)
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Articles

Trisomía 21: la investigación médica, principal motor de la inclusión y la innovación

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By Eugenio Barone, Luis Marín Sicilia, Antonio Cañadillas Muñoz
| El Debate (Spain) Verified
El 21 de marzo de 2025, en todo el mundo florecen iniciativas para celebrar la inclusión, la aceptación de las diferencias, la defensa continua de los derechos individuales y la promoción del bienestar de las personas con síndrome de Down.
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Modeling Alzheimer’s disease related phenotypes in the Ts65Dn mouse: impact of age on Aβ, Tau, pTau, NfL, and behavior

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By Eugenio Barone, Antonella Tramutola, Eric D. Hamlett
| Frontiers
1. Introduction Down syndrome (DS), or trisomy 21, affects one in 650–1,000 newborns globally (CDC, n.d.). Those with DS are highly predisposed to Alzheimer’s disease (AD), a condition referred to as DS with AD (DS-AD). With increased longevity, the prevalence of this condition has increased. Indeed, due to advances in medical care, the average life expectancy for those with DS has increased from ~5 years in the 1950s to ~54 years today (Yang et al., 2002; Presson et al., 2013; Iulita et al., 2022).
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