Euiyoung Bae on Muck Rack

Euiyoung Bae

South Korea
As seen in: Nature
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Articles

Structural investigation of QatB and QatC proteins in QatABCD anti-phage defense

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By Hyejin Oh, Euiyoung Bae
| Nature Verified
Abstract QatABCD is a widespread anti-phage defense system in prokaryotes comprising four protein components. QatC, a signature component, is homologous to QueC, an enzyme involved in nucleobase modification during queuosine biosynthesis. QatA and QatD are predicted to function as an ATPase and a nuclease, respectively, while QatB lacks identifiable sequence motifs. Here, we report the structural and functional characterization of QatB and QatC.
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Structural and functional evidence of bacterial antiphage protection by Thoeris defense system via NAD+ degradation

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By Donghyun Ka, Hyejin Oh, Eunyoung Park, Euiyoung Bae
| Nature Verified
Abstract The intense arms race between bacteria and phages has led to the development of diverse antiphage defense systems in bacteria. Unlike well-known restriction-modification and CRISPR-Cas systems, recently discovered systems are poorly characterized. One such system is the Thoeris defense system, which consists of two genes, thsA and thsB. Here, we report structural and functional analyses of ThsA and ThsB.
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