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Fabian Barthels on Muck Rack

Fabian Barthels

As seen in: Wiley Online Library, Royal Society of Chemistry, Dialnet - Universidad de La Rioja
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Articles

Direct‐to‐Biology: Streamlining the Path From Chemistry to Biology in Drug Discovery

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By Ariane F. Hübner, Fabian Barthels
| Wiley Online Library Verified
1 Introduction and Origin Direct-to-biology (D2B) denotes workflows in which newly, in-parallel synthesized compounds, often as crude reaction mixtures or minimally purified products, are tested directly in biological assays, collapsing the traditional make-purify-test cycle into rapid make-test loops.
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Advanced Isothermal Titration Calorimetry for Medicinal Chemists with ITCcalc

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By Stefan J. Hammerschmidt, Fabian Barthels, Annabelle Weldert, Christian Kersten
| Dialnet - Universidad de La Rioja
Stefan J. Hammerschmidt [1] ; Fabian Barthels [1] ; Annabelle C. Weldert [1] ; Christian Kersten [1] [1] Johannes Gutenberg-University, University Localización: Journal of chemical education, ISSN 0021-9584, Vol. 101, Nº 3, 2024, págs. 1086-1095 Idioma: inglés Texto completo no disponible (Saber más ...) Resumen Isothermal titration calorimetry (ITC) is the method of choice for thermodynamic binding profiling.
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