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Fabrizio Lombardo on Muck Rack

Fabrizio Lombardo

As seen in: Nature, Frontiers, MDPI
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Articles

Homing gene drives can transfer rapidly between Anopheles gambiae strains with minimal carryover of flanking sequences - Nature Communications

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By Poppy Pescod, Ruth Shelton, Fabrizio Lombardo
| Nature Verified
Abstract CRISPR-Cas9 homing gene drives are designed to induce a targeted double-stranded DNA break at a wild type allele (‘recipient’), which, when repaired by the host cell, is converted to the drive allele from the homologous (‘donor’) chromosome. Germline localisation of this process leads to super-Mendelian inheritance of the drive and the rapid spread of linked traits, offering a novel strategy for population control through the deliberate release of drive individuals.
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The buzz in the field: the interaction between viruses, mosquitoes, and metabolism

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By Daniel Ruzek, W. Robert Shaw, Fabrizio Lombardo
| Frontiers
Oshani C. Ratnayake1, Nunya Chotiwan1,2, Karla Saavedra-Rodriguez1 and Rushika Perera1* 1Center for Vector-borne Infectious Diseases, Dept.
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