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Fang Yin Lo

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Articles

Chemically induced skin tumors arise from long-lived stem cells of the upper hair follicle

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By Ke-Ting Shin, Justin Stewart, Eve Kandyba, Arnaud Jabouille, Ferriol Calvet, Yun Li Verified, Andrea Curtabbi, Joyce Shin, Reyno Delrosario, Jonathan M. Anzules, Di Wu, David Quigley Verified, Mark Taylor, Camila Zanette, Fang Yin Lo, Jacob Higgins, Jesse J. Salk, Nuria Lopez-Bigas, Allan Balmain, Diana Cristea
| Science Magazine Verified
Abstract Supplementary Materials References and notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Abstract The identification of the cancer cell of origin is a fundamental question in cancer biology. We used fluorescent lineage tracing of independent mouse skin stem cell populations, single cell transcriptomics, and Duplex sequencing, to identify the origin of chemically induced skin tumors.
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