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Fangyin Dai

As seen in: Nature, MDPI, Science Magazine, Royal Society of Chemistry
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Articles

Rare variant analysis reveals divergent genetic architectures of directly selected and correlated silkworm traits

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By Rui Gao, Chunlin Li, Dan Hu, Jing Wei, Ziwei Lv, Hai Hu, Kunpeng Lu, Minjin Han, Xiaoling Tong, Fangyin Dai
| Nature Verified
Abstract Correlational selection acts on combinations of correlated traits, driving multivariate phenotypic evolution, yet how it differentially shapes direct versus correlated traits remains unclear. Through rare variant association analysis of silkworm silk-yield traits, we reveal divergent genetic architectures of the direct traits cocoon shell weight (CSW) and ratio (CSR) versus the correlated traits cocoon and pupal weight (CW and PW).
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Stepwise evolution of a duplicated sugar transporter cluster into a flavonoid uptake system for silkworm cocoon coloration

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By Yaru Lu, Jiangwen Luo, Anjian Chen, Zhiruo Zhang, Yuhao Zhou, Minjin Han, Xiaoling Tong, Fangyin Dai
| Nature Verified
Abstract Gene duplication provides raw material for evolutionary innovation, yet how duplicated genes are progressively integrated into specialized biological systems remains poorly understood. Here we investigate a sugar transporter gene cluster in the silkworm that is associated with flavonoid accumulation underlying green cocoon pigmentation.
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Oral nanotherapeutics with enhanced mucus penetration and ROS-responsive drug release capacities for delivery of curcumin to colitis tissues

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By Yamei Huang, Shuangquan Gou, Nanxi Chen, Fangyin Dai
| Royal Society of Chemistry Verified
Oral nanotherapeutics with enhanced mucus penetration and ROS-responsive drug release capacities for delivery of curcumin to colitis tissues† Yamei Huang,‡ab Brandon S. B. Canup,‡c Shuangquan Gou,b Nanxi Chen,ad Fangyin Dai,ad Bo Xiao *abd and Changming Li b Author affiliations * Corresponding authors a State Key Laboratory of Silkworm Genome Biology, College of Sericulture, Textile and Biomass Sciences, Southwest University, Beibei, Chongqing 400715, P. R.
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