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Tailored Nanogel Network Topology Enables Clinical Ultrasound-Induced Mechanochemical Activation for In Vivo Therapy
1 Introduction Polymer mechanochemistry utilizes mechanical forces to selectively rearrange or cleave the mechanophores integrated into polymer systems [1]. Polymer mechanochemistry approaches has been widely applied in damage detection [2], optical sensing [3], self-regulating materials [4], and controllable molecular activation and release [5].
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