Fatima Abbas

Data is quickly becoming the new currency in healthcare led by organisations that prioritise secure storage, clinical interpretation, and the frictionless movement of data between patients and doctors. Dr. David Rhew, Global Chief Medical Officer & VP of Healthcare, Microsoft, USA, has spoken at large about engaging clinicians and patients in the digital age and about the power of data.

AM acetoxymethyl AMPAR AMPA receptors AP action potential AP-5 DL-2-amino-5-phosphonopentanoic acid KS Kolmogorov–Smirnov MF mossy fibre NBQX 2,3-dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide NMDAR NMDA receptors SNR signal-to-noise ratio SO stratum oriens SR stratum radiatum TTX tetrodotoxin VGCC voltage-gated Ca2+ channel 4-AP 4-aminopyridine (4-AP) ΔF/F0 fractional change of fluorescence ΔF/F0max maximum of ΔF/F0 1 Introduction Fluo-4 is a high affinity Ca2+ indicator...

1 Introduction Optical recordings of membrane potential (Vm) and intracellular ion transients are commonly used to investigate multisite neuronal activity [1, 2]. These recordings are measurements of fluorescence from a dye, which can be a genetically encoded protein [3] or an organic indicator [4].