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Integrating Artificial DNAzymes with Natural Enzymes on 2D MOF Hybrid Nanozymes for Enhanced Treatment of Bacteria‐Infected Wounds (Small 21/2024)
Duanping Sun Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006 China Key Specialty of Clinical Pharmacy, the First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, 510699 China Search for more papers by this author
Integrating Artificial DNAzymes with Natural Enzymes on 2D MOF Hybrid Nanozymes for Enhanced Treatment of Bacteria‐Infected Wounds
Conflict of Interest The authors declare no conflicts of interest. Supporting Information Filename Description smll202307256-sup-0001-SuppMat.pdf2.6 MB Supporting Information References 1, , , , , , Immunol. Rev. 2016, 273, 180. 2, , , , Ann. Clin. Microbiol. Antimicrob. 2013, 12, 22. 3, , , , , , , , , Cochrane Database. Syst. Rev. 2013, CD003543. 4, , , Acc. Chem. Res. 2020, 53, 1389. 5, , , , , Nano-Micro Lett. 2021, 13, 154. 6, , , , Pharmaceutics 2023, 15, 970. 7, , , , Coord. Chem. Rev. 2021, 439, 213929.
Aptamer and DNAzyme-Functionalized Cu-MOF Hybrid Nanozymes for the Monitoring and Management of Bacteria-Infected Wounds
Metal–organic frameworks (MOFs) with peroxidase (POD)-like activity have great potential for combating drug-resistant bacterial infections. However, the use of POD-like activities is severely limited by low oxygen levels and high levels of glutathione (GSH) within the microenvironment of bacterial infection.
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