Febu Elizabeth Joy

HLA human leukocyte antigen SCORTEN Severity-of-Illness Score for Toxic Epidermal Necrolysis SJS Steven-Johnson syndrome TCR T cell receptor TEN toxic epidermal necrolysis To the Editor, Steven-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, acute inflammatory skin reactions with a high mortality rate of ~20%–50% [1]. It is mainly related to medications, which can trigger an acute reaction causing extensive skin necrosis and detachment [2, 3].

Conflicts of Interest J.B. and F.E.J. were investigators in a Novartis-sponsored clinical study. J.B. holds shares of BionTech. M.S. is a consultant for Pfizer, Janssen, Eli-Lilly, Novartis, Abbvie, UCB, Celgene, Galderma, Leo, MenloTx, Sanofi, Regeneron. Grants were given by Pfizer, Novartis, Leo, and Galderma, and M.S. is a speaker for Pfizer, Janssen, Eli-Lilly, Novartis, Abbvie, UCB, Celgene, Galderma, Leo, MenloTx, Sanofi, Regeneron.