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Articles by Fei Gu
FABP4 as an immunometabolic hub in preeclampsia: from maternal-fetal interface to systemic inflammation
Abstract Preeclampsia (PE) is a multisystem vascular disease that occurs specifically during pregnancy, and the understanding of its pathogenesis is gradually shifting from the traditional “placental ischemia-endothelial injury” model to immunometabolic disorders. In this article, we propose a conceptual framework positioning fatty acid binding protein 4 (FABP4) as an immunometabolic hub in the pathogenesis of PE.
Deciphering microenvironmental heterogeneity by scalable Niche Guided Module Discovery
Abstract Spatial transcriptomics provides high-dimensional gene expression data while preserving spatial context, offering novel insights into tissue composition and heterogeneity. Each spot or cell in the spatial transcriptome could be reflected as gene modules influenced by its surrounding microenvironment, with module interactions vital for tissue architecture and function.
Experimental Study on the Compressive Behavior of Fiber-Reinforced Ceramsite Concrete
1. Introduction Ceramsite concrete is a kind of lightweight aggregate concrete (hereinafter referred to as LAC), which is prepared by replacing the coarse aggregate in traditional concrete with ceramsite.
Hepatic Flare Following Effective Antiretroviral Therapy Is Associated With HBsAg Seroclearance in HBV/HIV‐1 Co‐Infection
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description jmv70114-sup-0001-Supplementary_Figure_1_R.jpg163.8 KB Supporting information. jmv70114-sup-0002-Supplementary_Figure_2.jpg375 KB Supporting information. jmv70114-sup-0003-Supplementary_tables.docx31.1 KB Supporting information. jmv70114-sup-0004-supmat.docx12.2 KB Supporting information.
Identification of virus epitopes and reactive T-cell receptors from memory T cells without peptide synthesis - Communications Biology
Abstract Identifying epitopes and their corresponding T-cell receptor (TCR) sequences is crucial in the face of rapidly mutating viruses. Peptide synthesis is often required to confirm the exact epitope sequences, which is time-consuming and expensive. In this study, we introduce a scalable workflow to identify the exact sequences of virus epitopes and reactive TCRs targeting the epitopes from memory T cells.
Population-wide DNA methylation polymorphisms at single-nucleotide resolution in 207 cotton accessions reveal epigenomic contributions to complex traits | Cell Research
Abstract DNA methylation plays multiple regulatory roles in crop development. However, the relationships of methylation polymorphisms with genetic polymorphisms, gene expression, and phenotypic variation in natural crop populations remain largely unknown. Here, we surveyed high-quality methylomes, transcriptomes, and genomes obtained from the 20-days-post-anthesis (DPA) cotton fibers of 207 accessions and extended the classical framework of population genetics to epigenetics.
Vestigial like 4 regulates the adipogenesis of classical brown adipose tissue
Abstract Brown adipose tissue (BAT) is mammals' primary non-shivering thermogenesis organ, and the molecular mechanisms regulating BAT growth and adipogenesis are largely unknown. The Hippo-YAP pathway has been well-known for controlling organ size, and Vestigial like 4 (VGLL4) is a transcriptional regulator that modulates the Hippo-YAP pathway by competing against YAP for binding to TEAD proteins. In this study, we dissected the function of VGLL4 in regulating BAT development.
Pelvic Bone Marrow Sparing Intensity Modulated Radiotherapy Reduces the Bone Mineral Density Loss of Cervical Cancer Patients
Abstract To test the efficacy and feasibility of pelvic bone marrow sparing intensity modulated radiotherapy (PBMS-IMRT) in reducing bone density loss for patients with cervical cancer undergoing pelvic radiotherapy (RT). Non-surgical cervical cancer patients with Stage Ib2–IIIc cancer were randomly allocated into the PBMS group or the control group. The PBMS group additionally received PBM dose constraint.
Vestigial like 4 regulates the adipogenesis of classical brown adipose tissue
Abstract Brown adipose tissue (BAT) is mammals' primary non-shivering thermogenesis organ, and the molecular mechanisms regulating BAT growth and adipogenesis are largely unknown. The Hippo-YAP pathway has been well-known for controlling organ size, and Vestigial like 4 (VGLL4) is a transcriptional regulator that modulates the Hippo-YAP pathway by competing against YAP for binding to TEAD proteins. In this study, we dissected the function of VGLL4 in regulating BAT development.
Measuring HBV pregenomic RNA may be a potential biomarker to determine HBV functional cure in HIV/HBV‐co‐infected patients with HBsAg loss
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. REFERENCES 1, . Clinical implications of HIV and hepatitis B co-infection in Asia and Africa. Lancet Infect Dis. 2007; 7(6): 402-409. doi:10.1016/S1473-3099(07)70135-4 2, , , . HIV–HBV coinfection—a global challenge. N Engl J Med. 2012; 366(19): 1749-1752. doi:10.1056/NEJMp1201796 3, , , et al.
Sustainability | Free Full-Text | The Influence of Digital Transformation on the Reconfigurability and Performance of Supply Chains: A Study of the Electronic, Machinery, and Home Appliance Manufacturing Industries in China
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Creating Polyploid Escherichia Coli and Its Application in Efficient L‐Threonine Production
1 Introduction The cores of synthetic biology are to construct and implement new genetic systems and reshape natural biological systems. Advances in synthetic biology highlight a wide range of bio-based applications.[1] Designing an efficient microbial cell for high-value-added chemical production is a current research focus in synthetic biology.
Molecular Engineering Modulating the Singlet-Triplet Energy Splitting of Indolocarbazole-Based TADF Emitters Exhibiting AIE Properties for Nondoped Blue OLEDs with EQE of Nearly 20% | ACS Applied Materials & Interfaces
RETURN TO ARTICLES ASAPPREVOrganic Electronic D...Organic Electronic DevicesNEXT * Jinshan Wang Jiangsu Provincial Key Laboratory of Eco-Environmental Materials, School of Materials Science and Engineering, Yancheng Institute of Technology, Yancheng 224051, China *Email: wangjinshan@ycit.cn , Yuguang Yang Jiangsu Provincial Key Laboratory of Eco-Environmental Materials, School of Materials Science and Engineering, Yancheng Institute of Technology, Yancheng 224051, China , Fei Gu Jiangsu...
An Integrated Approach to Reservoir Characterization for Evaluating Shale Productivity of Duvernary Shale: Insights from Multiple Linear Regression
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The Interaction of Silent Reading Rate, Academic Vocabulary, and Comprehension Among Students in Grades 2-12
Article Alexandra N. Spichtig, Jeffrey P. Pascoe, Kristin M. Gehsmann, Kristin M. Gehsmann kgehsmann@vt.edu Virginia Tech, Blacksburg, VA, USA Search for more papers by this author Fei Gu, John D. Ferrara, PDF ShareShare Abstract This study examined silent reading rates (SRRs) in relation to students’ estimated academic vocabulary grade levels (EVGLs) and comprehension accuracy (Comprehension Items Correct; compIC).
linking academia, business and industry through research
Home Full-text access for editors Face spoof detection using feature map superposition and CNN by Fei Gu; Zhihua Xia; Jianwei Fei; Chengsheng Yuan; Qiang Zhang International Journal of Computational Science and Engineering (IJCSE), Vol. 22, No. 2/3, 2020 Abstract: Face biometrics have been widely applied for user authentication systems in many practical scenarios, but the security of these systems can be jeopardised by presenting photos or replays of the legitimate user.
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