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Xianhan Qin

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Articles

Deciphering microenvironmental heterogeneity by scalable Niche Guided Module Discovery

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By Chang Liu, Yuze Zhou, Longchen Xu, Tianhao Liu, Chen Tian, Jie Li, Fei Gu, Xun Lan, Xianhan Qin, Zibo Guan
| Nature Verified
Abstract Spatial transcriptomics provides high-dimensional gene expression data while preserving spatial context, offering novel insights into tissue composition and heterogeneity. Each spot or cell in the spatial transcriptome could be reflected as gene modules influenced by its surrounding microenvironment, with module interactions vital for tissue architecture and function.
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