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Fei Yin on Muck Rack

Fei Yin

As seen in: Nature, Wiley Online Library, arXiv, PLOS ONE, Frontiers, Frontiers in Public Health, MDPI, Taylor & Francis Online, BMC Cancer, Royal Society of Chemistry and
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Articles

Concurrent expression of glucose-6-phosphate dehydrogenase and secreted phosphoprotein 1 characterizes an aggressive and immunosuppressive tumor state in hepatocellular carcinoma

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By Guangjie Han, Lili Mi, Jianfei Shi, Jinfeng Wang, Fei Yin
| Frontiers
Abstract Introduction: Despite improved outcomes with combined hepatic arterial infusion chemotherapy (HAIC) and systemic therapy in hepatocellular carcinoma (HCC), therapeutic resistance is frequently driven by the tumor microenvironment. We aimed to explore biological features associated with therapeutic resistance in HCC. Methods: We integrated single-cell transcriptomics of a therapy-progressive lesion with large-scale bulk transcriptomic modeling and independent clinical validation.
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Clcn6 mRNA and ClC-6 protein expression in mouse central nervous system

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By Xiaoshuang Cao, Hailan He, Fei Yin, Jing Peng
| Nature Verified
Abstract To investigate the expression patterns of Clcn6 mRNA and ClC-6 protein in postnatal mouse of distinct region of central nervous system (CNS) and developmental stages. Distinct CNS regions, including cerebral cortex, hippocampus, cerebellum, brainstem, olfactory bulb, hypothalamus, corpus striatum, thalamus and spinal cord, were dissected from C57BL/6 wildtype mice at different developmental stages, including P0, P7, P14, P30, and P60. Total RNA and protein were extracted.
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Repeated restraint stress enhances visual plasticity through locus coeruleus (LC)-V1 projection in adult mice

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By Haiping Hu, Xi Kuang, Fei Yin, Wei Meng, Yupeng Yang
| Nature Verified
Abstract Stress modulates a broad range of brain functions, including the visual system. However, the specific neural mechanisms by which stress regulates function and plasticity in the adult visual system remain unclear. This study demonstrates that repeated restraint stress selectively enhances ocular dominance plasticity (ODP) in the primary visual cortex (V1) of adult mice. This stress-induced reinstatement of ODP depends on noradrenergic (NE) signaling.
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