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Fei Yin on Muck Rack

Fei Yin

As seen in: Nature, Wiley Online Library, arXiv, PLOS ONE, Frontiers, Frontiers in Medicine, Frontiers in Immunology, Frontiers in Public Health, MDPI, Taylor & Francis Online and
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Articles

Case Report: Neurosyphilis with a paraparetic Guillain-Barré-spectrum phenotype and CSF-detected anti-GT1a IgG: an infection-autoimmunity diagnostic challenge

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By Xing Zhao, Yizhi Zhang, Wenjing Xie, Fei Yin
| Frontiers in Immunology
Abstract Background: Active central nervous system (CNS) infection can resemble acute immune polyradiculoneuropathy, and the two processes may coexist. We describe a patient with neurosyphilis, rapidly progressive paraparetic weakness, and anti-GT1a IgG detected in cerebrospinal fluid (CSF) but not serum by a qualitative line immunoblot. Case presentation: A 41-year-old man developed rapidly progressive paraparesis, urinary retention, and left abducens palsy.
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Development and validation of an interpretable machine-learning model for predicting treatment failure in severe trauma patients

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By Qiang Shi, Yun Liu, Jiahui Shen, Fei Yin, Zhenguo Qiao, Jun L Zhou, Deli Xu, Teng Zhang, Chengzhi Xu, Xie Shen
| Frontiers in Medicine
Abstract Objective: This study aims to develop and validate machine learning (ML) models for predicting treatment failure in trauma patients using comprehensive clinical and laboratory variables, and to identify key prognostic features. Methods: A retrospective cohort of 318 trauma patients was included.
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Concurrent expression of glucose-6-phosphate dehydrogenase and secreted phosphoprotein 1 characterizes an aggressive and immunosuppressive tumor state in hepatocellular carcinoma

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By Guangjie Han, Lili Mi, Jianfei Shi, Jinfeng Wang, Fei Yin
| Frontiers
Abstract Introduction: Despite improved outcomes with combined hepatic arterial infusion chemotherapy (HAIC) and systemic therapy in hepatocellular carcinoma (HCC), therapeutic resistance is frequently driven by the tumor microenvironment. We aimed to explore biological features associated with therapeutic resistance in HCC. Methods: We integrated single-cell transcriptomics of a therapy-progressive lesion with large-scale bulk transcriptomic modeling and independent clinical validation.
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