Feimei Liu

eLife Assessment This important study presents an alternative platform for nanobody discovery using phage-displayed synthetic libraries. The evidence supporting the platform, which is used to isolate and validate nanobodies targeting Drosophila secreted proteins, is compelling. By making the library openly accessible, this provides an excellent resource to the wider scientific community.

Correction to: Nature Medicine https://doi.org/10.1038/s41591-021-01355-0, published online 5 May 2021. In the version of this article initially published, two author names (Alfred Lee and Saad Omer) were missing the middle initial. The correct names are ‘Alfred I. Lee’ and ‘Saad B. Omer’ (respectively). The errors have been corrected in the HTML and PDF versions of the article. Author information Author notes These authors contributed equally: Carolina Lucas, Jon Klein.

Abstract COVID-19 manifests with a wide spectrum of clinical phenotypes that are characterized by exaggerated and misdirected host immune responses1,2,3,4,5,6. Although pathological innate immune activation is well-documented in severe disease1, the effect of autoantibodies on disease progression is less well-defined.