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Secondary Metabolites from the Genus Eurotium and Their Biological Activities
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Impact of clozapine monotherapy on gut microbiota and metabolism in people with schizophrenia
1. Introduction Second-generation antipsychotics are currently the mainstay of treatment for schizophrenia. Clozapine is considered the prototype and representative of second-generation antipsychotics (Stahl, 2013). Clozapine is significantly better than other antipsychotics in reducing psychotic symptoms, violence, and persistent aggression in patients with schizophrenia (Frogley et al., 2012).
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