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MRI radiomics reveals peritumoural distance associations with IDH and MGMT status in gliomas
Abstract To develop a non‑invasive multiparametric MRI radiomics model for predicting IDH mutation and MGMT promoter methylation in adult diffuse gliomas, systematically evaluating different peritumoural regions (3 mm, 5 mm, 10 mm) and sequence combinations contrast-enhanced T1-weighted imaging (T1WI-CE), T2-weighted fluid-attenuated inversion recovery (T2-FLAIR), and arterial spin labeling (ASL) with multi‑centre external validation.
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