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Fenying Zang on Muck Rack

Fenying Zang

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Articles

Age-related changes in behavioural and neural variability in a decision-making task

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By Anup Khanal, Sonja Forster, Anne Churchland, Anne E. Urai, Fenying Zang
| Nature Verified
Abstract Age-related cognitive decline in learning and decision-making may arise from increased variability of neural responses. Here, we investigated how ageing affects behavioural and neural variability by recording >18,000 neurons across 16 brain regions (including cortex, hippocampus, thalamus, midbrain, and basal ganglia) in younger and older mice performing a visual decision-making task. Older mice showed more variable response times, reproducing a common finding in human ageing studies.
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