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Tacrolimus Concentration in Pediatric Compounded Suspensions Under Conditions Mimicking Real‐Life Use
API active pharmaceutical ingredient BBE bottle-bottom effect CHUSJ Centre Hospitalier Universitaire Sainte-Justine TCS tacrolimus compounded suspension UHPLC ultra-high performance liquid chromatography UV ultraviolet 1 Introduction Tacrolimus is a calcineurin inhibitor that has become essential for immunosuppression in children undergoing solid organ transplantation [1].
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