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Fernando Ambriz-Barrera on Muck Rack

Fernando Ambriz-Barrera

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Methylation marks in blood DNA reveal breast cancer risk in patients fulfilling hereditary disease criteria - npj Precision Oncology

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By Javier Oliver, Fernando Ambriz-Barrera
| Nature Verified
Abstract Less than 15–20% of patients who meet the criteria for hereditary breast and ovarian cancer (HBOC) carry pathogenic coding genetic mutations, implying that other molecular mechanisms may contribute to the increased risk of this condition. DNA methylation in peripheral blood has been suggested as a potential epigenetic marker for the risk of breast cancer (BC).
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