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Fernando Ferreira Costa

As seen in: MDPI, Journal of Pharmacology and Experimental Therapeutics
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Articles

Accompanying Hemoglobin Polymerization in Red Blood Cells in Patients with Sickle Cell Disease Using Fluorescence Lifetime Imaging

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By Joao Batista Florindo, Fernando Ferreira Costa, Irene Lorand-Metze, Konradin Metze
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Accompanying Hemoglobin Polymerization in Red Blood Cells in Patients with Sickle Cell Disease Using Fluorescence Lifetime Imaging

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By Fernando Ferreira Costa, Irene Lorand-Metze, Konradin Metze, Joao Batista Florindo
| preprints.org
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 2 October 2024 / Approved: 3 October 2024 / Online: 3 October 2024 (12:09:46 CEST) Borges da Silva, F. A.; Florindo, J. B.; Mattos, A. C. D.; Costa, F. F.; Lorand-Metze, I.; Metze, K. Accompanying Hemoglobin Polymerization in Red Blood Cells in Patients with Sickle Cell Disease Using Fluorescence Lifetime Imaging. Preprints 2024, 2024100252. https://doi.org/10.20944/preprints202410.0252.v1 Borges da Silva, F.
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Nitric Oxide Resistance in Priapism Associated with Sickle Cell Disease: Mechanisms, Therapeutic Challenges, and Future Directions.

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By Dalila Pereira, Fabiano Calmasini, Arthur L Burnett, Fernando Ferreira Costa
| Journal of Pharmacology and Experimental Therapeutics
Abstract Patients with sickle cell disease (SCD) display priapism, a prolonged penile erection in the absence of sexual arousal. The current pharmacological treatments for SCD-associated priapism are limited and focused on acute interventions rather than prevention. Thus, there is an urgent need for new drug targets and preventive pharmacological therapies for this condition.
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