Ferran Barrachina
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Translation of a human induced pluripotent stem cell-derived ovarian support cell product to a Phase 3 enabling clinical grade product for in vitro fertilization treatment
B.P., F.B., A.D.N., M.J., S.K., S.P., M.M., A.B.F., C.L., P.B., and C.C.K. are/were shareholders in the for-profit biotechnology company Gameto Inc while performing this work. C.C.K., S.P., M.M., B.P., and A.D.N. are listed on a patent covering the use of OSCs for IVM: U.S. Provisional Patent Application No. 63/492,210.
Proton-secreting cells modulate mucosal immune surveillance in the male reproductive tract
Abstract Proton-secreting cells in various organs, such as the kidney and epididymis, regulate pH balance, maintaining cellular homeostasis, and supporting key physiological processes. More recently, these specialized cells have emerged as key contributors to mucosal immunity, orchestrating immune activation. Epididymitis is an inflammatory condition that significantly impacts male fertility, often due to a lack of diagnosis and treatment.
Reproducible differentiation of pure ovarian support cells from clinical-grade hiPSCs as a novel infertility treatment
Abstract In vitro maturation (IVM) is an infertility treatment used during in vitro fertilization (IVF) procedures in which immature oocytes are matured outside the body, limiting the excessive hormone doses required for retrieval of ready-to-fertilize oocytes.
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