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An interaction graph approach to gain new insights into mechanisms that modulate cerebrovascular tone - Communications Biology

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By Sergio Dempsey, Finbar Argus
| Nature Verified
Abstract Mechanisms to modulate cerebrovascular tone are numerous, interconnected, and spatially dependent, increasing the complexity of experimental study design, interpretation of action-effect pathways, and mechanistic modelling. This difficulty is exacerbated when there is an incomplete understanding of these pathways. We propose interaction graphs to break down this complexity, while still maintaining a holistic view of mechanisms to modulate cerebrovascular tone.
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