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Fiyad Alsarmi on Muck Rack

Fiyad Alsarmi

As seen in: BioRxiv
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Articles

AMPK activation prevents HCC development through inhibition of HNF4a activity

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By Zhen Sun, Bernard Linares, Cassidy Urdiales, Fiyad Alsarmi
| BioRxiv
Abstract Hepatocellular carcinoma (HCC) is a major cause of cancer-related mortality and is largely driven by metabolic disorders such as obesity and Type 2 Diabetes. The AMP-activated protein kinase (AMPK) is a master regulator of metabolism, coordinating glucose and lipid metabolism, and its activation has been proposed as a therapeutic strategy for treating metabolic disorders.
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