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Flávio Lemos Matassoli on Muck Rack

Flávio Lemos Matassoli

As seen in: Science Magazine, BioRxiv
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Articles

SARS-CoV-2 variant booster vaccination and infection alter the breadth of the memory B cell repertoire

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By Kyeongseok Jeon, Axel A Guzmán-Solís, Rory Malek, Flávio Lemos Matassoli, Kyle Gordon, Geoffrey D. Shimberg, Grace Mantus, Abby Spangler, Ankita J. Chopde, I-Ting Teng, Tongqing Zhou, Bob Lin, Robin Carroll, Rachel Kazmierski, Lingshu Wang, Christine M. Posavad, Nadine Rouphael, Angela R. Branche, Paul Roberts, Leonid Serebryannyy, Sarah Andrews
| Science Magazine Verified
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary As SARS-CoV-2 continues to evolve in response to vaccine- and infection-induced immune pressure, vaccines will need to be updated to match currently circulating strains. Here, Malek et al. evaluated what impact a SARS-CoV-2 Omicron variant booster vaccine had on the overall memory B cell (MBC) response to SARS-CoV-2.
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Computationally designed stem-epitope mimetics elicit broadly reactive antibodies

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By Andreas Scheck, Flávio Lemos Matassoli, Sarah Wehrle, Laura Reusch
| BioRxiv
Abstract Broad protection against diverse influenza viruses can be conferred by broadly neutralizing antibodies (bnAbs) targeting a conserved site on the hemagglutinin (HA) stem domain. However, the low immunogenicity of this antigenic region hinders the robust induction of such antibodies. Here, we showcase a structure-based immunogen design strategy focusing on the surface mimicry of antigenic sites.
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Adjuvanted SARS-CoV-2 spike protein vaccination elicits long-lived plasma cells in nonhuman primates

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By Atika Malique, Madhu S. Prabhakaran, Emily Wheeler, Flávio Lemos Matassoli
| Science Magazine Verified
Research Article CORONAVIRUS Madhu Prabhakaran https://orcid.org/0000-0002-1981-9054, Flavio Matassoli https://orcid.org/0009-0000-5559-8781, [...] , David Leggat https://orcid.org/0000-0003-4019-7170, Abigayle Hoover https://orcid.org/0000-0002-1773-1438, [...] , Abhinaya Srikanth, Weiwei Wu, Amy R. Henry amy.ransier@nih.gov, Jennifer Wang, Bob C. Lin https://orcid.org/0000-0002-1373-1406, [...] , I-Ting Teng https://orcid.org/0000-0002-4704-7100, Chaim A.
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