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Florence Bartlett-Tomasetig on Muck Rack

Florence Bartlett-Tomasetig

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Stiff matrix impairs cytotoxic T lymphocyte function at multiple levels

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By Shunya Nakayama, Jinheum Park, Mir Hadi Seyedzadeh, Eric Y Du, Kristopher A. Kilian, Katharina Gaus, Jesse Goyette, J. Justin Gooding, Florence Bartlett-Tomasetig, Gaia M. N. Javier
| Science Magazine Verified
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Cytotoxic T lymphocytes (CTLs) play a pivotal role in antitumor immunity via inducing apoptosis in cancer cells. However, their effector functions can be compromised by the perturbations in the tumor microenvironment (TME).
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