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Francesca Barcellini

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Position-independent emergence of neocortical neuron molecular identity, connectivity and function - Nature Neuroscience

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By Sergi Roig-Puiggros, Maëlle Guyoton, Giulio Matteucci, Alessandra Panzeri, Charlie G. Foucher, Esther Klingler, Fiona Francis, Valerio Zerbi, Camilla Bellone, Marat MINLEBAEV, Sami El-Boustani, Dmitrii Suchkov, Aurélien Fortoul, Francesca Barcellini, Jean-Bernard Manent
| Nature Verified
Abstract Brain architectures vary widely across species, yet how neuronal positioning constrains the type of circuits that can be made, and their function, remains poorly understood. Here we examine how neuronal position affects molecular identity, connectivity and function by studying Eml1 knockout mice, which exhibit abnormally located (heterotopic) neurons beneath the cortex.
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