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A Concise and Divergent Approach to the Naturally Occurring Tetracyclic Clavine Alkaloids (+)-Lysergol, (+)-Lysergine, and (+)-Isolysergine
Introduction Click to copy section linkSection link copied! Ergot alkaloids (EAs) are a class of pharmacologically active indole compounds biosynthetically derived from l-tryptophan and dimethylallyl pyrophosphate, followed by cyclization. (1) They are specialized fungal metabolites that are important in agriculture and serve as the basis for several pharmaceuticals.
Enantioselective organocatalytic strategies to noncanonical α-amino acids
Enantioselective organocatalytic strategies to noncanonical α-amino acids Organocatalytic asymmetric synthesis has evolved over the years and continues to attract the interest of many researchers worldwide. Enantiopure noncanonical amino acids (ncAAs) are valuable building blocks in organic synthesis, medicinal chemistry, and chemical biology.
A Short Synthesis of (−)‐6,7‐Secoagroclavine via Metal‐Free Reductive Coupling
Conflict of interests The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
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