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Francesca Odoardi

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Articles by Francesca Odoardi

Use of animal models to understand CNS neuroimmunology — guidance from the International Society for Neuroimmunology White Paper Task Force

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By Jennifer L Gommerman, Katerina Akassoglou, Sergio Baranzini, Burkhard Becher, Fabienne Brilot, Gonçalo Castelo-Branco, Shannon Dunn, Maryam Faiz, Alexander Flügel, Nader Ghasemlou, Erin Gibson, Judith M. Greer, Denis Gris, Cole Harrington, Steffen Jung, Lorraine V. Kalia, Thomas Korn, Gurumoorthy Krishnamoorthy, Roland S. Liblau, Francesca Odoardi, Laura Piccio, Anne-Katrin Pröbstel, Francisco J. Quintana, Valeria Ramaglia, Manu Rangachari, Olga Rojas, Marc J. Ruitenberg, Scott Russo, Dorothy P. Schafer, Benjamin Segal, Jana Vukovic, Chao Wang, Michael Wheeler, Heinz Wiendl, V. Wee Yong, Frauke Zipp, Veronique Miron
| Nature Verified
Abstract Neuroimmunology is a rapidly expanding field in which many breakthroughs have been fuelled by studies in animal models that capture aspects of human neurological disease. However, the variety of animal models available, with their relative merits and drawbacks, is not well documented in the literature, posing a hurdle for scientists who are venturing into the world of neuroimmunology.
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Distinct roles of the meningeal layers in CNS autoimmunity - Nature Neuroscience

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By Jonas Franz, Kari Alitalo, Francesca Odoardi
| Nature Verified
Abstract The meninges, comprising the leptomeninges (pia and arachnoid layers) and the pachymeninx (dura layer), participate in central nervous system (CNS) autoimmunity, but their relative contributions remain unclear. Here we report on findings in animal models of CNS autoimmunity and in patients with multiple sclerosis, where, in acute and chronic disease, the leptomeninges were highly inflamed and showed structural changes, while the dura mater was only marginally affected.
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