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Francoise Bex

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Articles

FOXP1 is a key regulator of quiescence in healthy human CD3+CD4+ T Cells and is constitutively repressed in CD3-CD4+ T cells from patients with lymphoproliferative disorders - Garaud - 2016 - European Journal of Immunology - Wiley Online Library

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By Soizic Garaud, Florence Roufosse, Pushpamali Silva, Chunyan Gu-Trantien, Jean-Nicolas Lodewyckx, Hugues Duvillier, Sarah Dedeurwaerder, Martin Bizet, Matthieu Defrance, Francois Fuks, Francoise Bex, Karen Willard-Gallo
| AIChE Journal Verified
The forkhead box P1 (FOXP1) transcription factor has been shown to regulate the generation and maintenance of quiescent naïve murine T cells. In humans, FOXP1 expression has been correlated with overall survival in patients with peripheral T-cell lymphoma (PTCL), although its regulatory role in T-cell function is currently unknown. We found that FOXP1 is normally expressed in all human leukocyte subpopulations.
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