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Françoise Debart

As seen in: ACS Publications, Science Magazine
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Articles

In vitro liquid-liquid phase separation induced by respiratory syncytial virus proteins and RNA

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By Dennis Wylie, Masahiro Yoshida, Wouter J. Holman, Vincent Basse, Tanushree Agarwal, Tomas Sneideris, Charles-Adrien Richard, Joris Troussier, Jean-Jacques Vasseur, Françoise Debart, Jean-François Éléouët, Ella de Csillery, Tuomas Knowles, Marie Galloux
| Science Magazine Verified
Abstract Respiratory syncytial virus (RSV) causes severe respiratory infections, with viral replication occurring in cytoplasmic membraneless viral factories formed by liquid-liquid phase separation (LLPS). The interactions among the RSV nucleoprotein N, phosphoprotein P, transcription factor M2-1, and RNA drive these condensates. Here, we used a microfluidic PhaseScan platform, together with biochemical and cellular assays, to systematically characterize LLPS involving RSV proteins and RNA.
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Synthesis and Base-Pairing Properties of Oligonucleotides Containing 5′-(R)- and 5′-(S)-C-Aryl-thymidine

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By Jean-Jacques Vasseur, Françoise Debart, Marcel Hausdorff, Mary Anne Maverick
| ACS Publications
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The C-Terminal Domain of the Sudan Ebolavirus L Protein Is Essential for RNA Binding and Methylation

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By Université Aix-Marseille, Baptiste Martin, Coralie Valle, Françoise Debart
| Journal of Virology Verified
Genome Replication and Regulation of Viral Gene Expression Coralie Valle, Baptiste Martin, Françoise Debart, Jean-Jacques Vasseur, Isabelle Imbert, Bruno Canard, Bruno Coutard, Etienne Decroly Rebecca Ellis Dutch, Editor DOI: 10.1128/JVI.00520-20 ABSTRACT The large (L) protein of Ebola virus is a key protein for virus replication.
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