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Fransisca Leonard

As seen in: Frontiers
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Articles

Advances in dendritic cell targeting nano-delivery systems for induction of immune tolerance

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By Marco P. Monopoli, Nick Giannoukakis, Fransisca Leonard
| Frontiers
1 Introduction DCs were discovered in the early 1970s, since then their biological properties have been extensively studied. To date, they are known as the “gatekeepers of the immune system” due to their ability to maintain immune homeostasis by activating adaptive immunity or promoting tolerance (Steinman and Cohn, 1973; Steinman and Cohn, 1974; Puhr et al., 2015).
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