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Frederic Chano

As seen in: Nature
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Articles by Frederic Chano

5′ leader defects drive persistent HIV-1 viremia on long-term ART

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By Angelica Camilo-Contreras, Filippo Dragoni, Feng Yue, Vitaliy A. Matveev, Jackson R Foley, Jianwei Zhang, Jun S. Lai, Claude Fortin, Cécile Tremblay, Joel N Blankson, Sonya Krishnan, Ethel D. Weld, Matthew M Hamill, Christopher J Hoffmann, Eileen P. Scully, Joyce Jones, Andrea Cox, Wissam El Atrouni, Beverly E. Sha, Janet D. Siliciano, Robert F. Siliciano, Robert Reinhard, Jesper D. Gunst, Mario A. Ostrowski, Frank Maldarelli, Colin M. Kovacs, Francesco Simonetti, Julia R. Box, Yan Wei Mok, Marlene DeSousa, Zachary Mulcare, Zachary Bakewell, Sebastien Poulin, Frederic Chano, Christie Basseth
| Nature Verified
Abstract Traces of HIV-1 RNA can persist in plasma despite long-term suppressive antiretroviral therapy (ART). Some individuals develop nonsuppressible viremia (NSV), characterized by detectable HIV-1 RNA that raises concerns for virological failure, pathogenesis, and transmission. The sources of NSV remain poorly defined, in part due to limited tools to characterize plasma HIV-1 RNA.
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