Friedhelm R. Schuster on Muck Rack

Friedhelm R. Schuster

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Articles

Excellent survival after allogeneic HSCT in screened SCID patients and donor type dependent naïve T cell reconstitution

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By Kajetan Trojovsky, Arndt Borkhardt, Roland Meisel, Sujal Ghosh, Friedhelm R. Schuster, Hans-Jürgen Laws, Olga Kyrillopoulou
| Nature Verified
To the Editor Severe combined immunodeficiency (SCID) is defined by profound numeric or functional T cell deficiency and, without treatment almost all patients die within the first year of life due to severe infections or immune dysregulation [1]. Early and sufficient T cell restoration, typically achieved by allogeneic hematopoietic stem cell transplantation (HSCT), is essential, while gene therapy or enzyme replacement are options for selected entities [2].
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