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Fukang Mao

As seen in: Frontiers in Medicine
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Articles

Spatial niche remodeling of senescent liver-resident immune cells and its role in chronic liver diseases

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By Fukang Mao, Keji Shan
| Frontiers in Medicine
Abstract The liver serves the triple functions of metabolism, detoxification, and immune surveillance. Its unique immune microenvironment is shaped by continuous exposure to gut-derived antigens, pathogen-associated molecular patterns (PAMPs), and metabolites arriving via the portal vein, necessitating a delicate equilibrium between immune tolerance and effector activation.
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