Funda Yilmaz

Discussion Cholangiocarcinoma remains a challenging malignancy characterized by poor prognosis, delayed diagnosis, and limited treatment options, with surgical resection being the only curative approach available to approximately one-third of patients at diagnosis (8).

Abstract Endomyocardial biopsy (EMB) screening represents the standard of care for detecting allograft rejections after heart transplant. Manual interpretation of EMBs is affected by substantial interobserver and intraobserver variability, which often leads to inappropriate treatment with immunosuppressive drugs, unnecessary follow-up biopsies and poor transplant outcomes.