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G. Barra on Muck Rack

G. Barra

As seen in: Annals of Oncology
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Articles

Anti-PD1 therapy effects on T cell repertoire and functions in patients with NSCLC cancer: a preliminary study to identify biomarkers of efficacy

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By C. M. Della Corte, F. Papaccio, G. Barra, G. Pasquale
| Annals of Oncology Verified
Background: Immune responses have a pivotal role in protecting against tumors, since conventional chemotherapy may effectively treat cancer but its efficacy is compromised by tumor relapse. Chemotherapy “per se” can have immunostimulatory effects, and the ability to sustain an antitumor T cell response activate host immunity and prevent tumor re-growth. Anti-PD1 antibodies may be used in clinics to boost immune responses through the blocking of an inhibitor receptor on T cells.
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