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Molecular profiling and access to treatment for rare cancers in Europe
Abstract Arcagen is a clinical study proposing a comprehensive analysis of molecular and clinical characteristics of rare adult solid cancers (11 domains: sarcomas, gynecology, uro-genital, GI, NET, head and neck, thoracic, skin and eyes, CNS and CUP) across Europe, utilizing the EORTC-SPECTA platform with the EURACAN ERN. This study enrolled 1235 advanced stage patients.
The role of the molecular tumor board: learnings from the ROME trial
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Abstract Precision Oncology transformed cancer therapy by personalizing treatment based on specific tumor molecular alterations. However, the increasing complexity of genomic and multi-omic data challenges clinical interpretation. Molecular Tumor Boards (MTBs) are critical for integrating expertise and translating genomic profiling into treatment recommendations.
By P. Marchetti, G. Curigliano, S. Lonardi, V. Guarneri, U. De Giorgi, P. A. Ascierto, G. Blandino, M. Aglietta, C. Cremolini, P. F. Conte, S. Verkhovskaia, A. Fabbri, F. Puglisi, D. Marino, F. Cappuzzo, G. Giannini, U. Malapelle, F. Mazzuca, M. Nuti, G. Pruneri, C. Pinto, E. Maiello, A. C. Russo, R. Berardi, G. Lombardi, G. Masi, L. Bonanno, N. Martini, A. Botticelli, C. B. Westphalen, M. Biffoni, S. Scagnoli, L. Fornaro, G. D’Amati, E. Crimini, M. Ceracchi, S. Pisegna, R. Bordonaro, S. Bracarda, G. Butturini, L. Del Mastro, A. DeCensi, F. De Galitiis, E. Fenocchio, S. Gori, A. Pessino, D. Pozzessere, S. Tamberi, A. Zambelli, E. Capoluongo, B. Cerbelli, M. Simmaco, L. Strigari, G. Tonini, A. Savarese, V. Adamo, D. Quaresmini, P. Tagliaferri, P. Damiano, B. Urbini, C. Bengala, E. Zaffignani, A. Tosoni, L. Buffoni, C. Mucciarini, A. Piancastelli, V. Vanella, F. Mannozzi
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Nature
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Attribution of Flood Forecasting Errors From a Multi‐Model Perspective in Milan Urbanized River Basins
COSMO-LAMI COnsortium for Small-scale MOdelling-Limited Area Model for Italy CSA continuous slope area CSNO Canale Scolmatore Nord-Ovest EPSs ensemble forecast systems FEST-WB flash-flood event-based spatially-distributed rainfall-runoff transformation—water balance mode GFS Global Forecasting System GRIB GRIdded Binary HEPSs hydrological ensemble prediction systems CNR-ISAC Institute of Atmospheric Sciences and Climate of the National Research Council IQR interquartile range LAMs limited...
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