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Articles by G. Rees
Longitudinal MR imaging after unilateral MR-guided focused ultrasound thalamotomy: clinical and radiological correlation
1. Introduction Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy has demonstrated successful treatment of medication-refractory tremor in essential tremor (ET) (1, 2). This technique uses transcranial acoustic energy to ablate the ventral intermediate (Vim) nucleus of the thalamus, allowing for an incisionless approach in an awake patient to relieve debilitating tremor.
Characterizing brain dynamics during ketamine-induced dissociation and subsequent interactions with propofol using human intracranial neurophysiology
Nature Communications, Apr 2023 This is a preview of a remote PDF: https://www.nature.com/articles/s41467-023-37463-3.pdf Tian, Fangyun, Lewis, Laura D., Zhou, David W., Balanza, Gustavo A., Paulk, Angelique C., Zelmann, Rina, Peled, Noam, Soper, Daniel, Santa Cruz Mercado, Laura A., Peterfreund, Robert A., Aglio, Linda S., Eskandar, Emad N., Cosgrove, G. Rees, Williams, Ziv M., Richardson, R. Mark, Brown, Emery N., Akeju, Oluwaseun, Cash, Sydney S., Purdon, Patrick L..
Closed-loop enhancement and neural decoding of cognitive control in humans - Nature Biomedical Engineering
Abstract Deficits in cognitive control—that is, in the ability to withhold a default pre-potent response in favour of a more adaptive choice—are common in depression, anxiety, addiction and other mental disorders. Here we report proof-of-concept evidence that, in participants undergoing intracranial epilepsy monitoring, closed-loop direct stimulation of the internal capsule or striatum, especially the dorsal sites, enhances the participants’ cognitive control during a conflict task.
A Prospective Trial of Magnetic Resonance guided Focused Ultrasound Thalamotomy for Essential Tremor: Results at the 2-year Follow-up
Objective: Magnetic resonance guided focused ultrasound (MRgFUS) has recently been investigated as a new treatment modality for essential tremor (ET), but the durability of the procedure has not yet been evaluated. This study reports results at a 2- year follow-up after MRgFUS thalamotomy for ET.
A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor
The use of ultrasound energy for the creation of discrete intracranial lesions (hereafter referred to as lesioning) has been of interest since the middle of the 20th century. 17 Initial procedures required craniotomy to establish an acoustic window for the treatment of movement disorders and psychiatric conditions.
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