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G. Tuba Barut

As seen in: Nature, Wiley Online Library
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Articles

Water Mass Assemblages and Nutrient Dynamics in Nares Strait: A Multiyear Perspective

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By G. Tuba Barut, T. M. Burgers, J.-É. Tremblay, N. Schiffrine
| Wiley Online Library Verified
1 Introduction Nares Strait, located between the northern Canadian Arctic Archipelago and Greenland, is a crucial gateway for the exchange of heat and freshwater with the North Atlantic Ocean (Münchow et al., 2006; Rudels et al., 1996). This region is a key sentinel for studying Arctic changes, which have significant consequences for the global climate system.
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A safe, effective and adaptable live-attenuated SARS-CoV-2 vaccine to reduce disease and transmission using one-to-stop genome modifications - Nature Microbiology

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By Jacob Schön, G. Tuba Barut, Nico Halwe, Lorenz Ulrich, Jenna Kelly, Melanie Brugger, Claudia Wylezich, Adriano Taddeo, Etori Aguiar Moreira, Llorenç Grau-Roma, Ann Kathrin Ahrens, Kore Schlottau, Angele Breithaupt, Lea Almeida, Lisa Thomann, Hanspeter Stalder, Silvio Steiner, Marco P. Alves, Charaf Benarafa, Donata Hoffmann, Martin Beer, Bettina Salome Trüeb, Tobias Britzke, Jana Kochmann, Sarah Ochsenbein, Kimberly Schmied, Jörg Jores
| Nature Verified
Abstract Approved vaccines are effective against severe COVID-19, but broader immunity is needed against new variants and transmission. Therefore, we developed genome-modified live-attenuated vaccines (LAV) by recoding the SARS-CoV-2 genome, including ‘one-to-stop’ (OTS) codons, disabling Nsp1 translational repression and removing ORF6, 7ab and 8 to boost host immune responses, as well as the spike polybasic cleavage site to optimize the safety profile.
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SARS-CoV-2 biology and host interactions - Nature Reviews Microbiology

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By Silvio Steiner, Annika Kratzel, Etori Aguiar Moreira, Jenna Kelly, G. Tuba Barut, Reto M. Lang, Lisa Thomann
| Nature Verified
Abstract The zoonotic emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected our society. The rapid spread and continuous evolution of new SARS-CoV-2 variants continue to threaten global public health.
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