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Gabriel Pinheiro Modolo on Muck Rack

Gabriel Pinheiro Modolo

As seen in: MDPI
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JCM | Free Full-Text | Effect of a Physical Exercise Program on the Inflammatory Response, Cardiac Functions, Functional Capacity, and Quality of Life in Patients with Sickle Cell Disease

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By Gustavo José Luvizutto, Rodrigo Bazan, Péricles Sidnei Salmazo, Gabriel Pinheiro Modolo
| MDPI
1. Introduction SCD is an autosomal codominant disease caused by abnormal beta-globin alleles that carry a sickle cell mutation in the HBB gene. It is one of the most common monogenic disorders in hematology [1]. The pathophysiology of SCD is related to structural alterations that occur in sickle-shaped red blood cells (HbS) due to structural changes in chromosome 11 [2].
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