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Gaël Cobraiville on Muck Rack

Gaël Cobraiville

As seen in: Nature, ACS Publications
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Articles

Assessing Surface Binding Events on Golgi Microsomes Isolated from Cancer Cells by Capillary Electrophoresis Click to copy article link Article link copied!

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By Clara Davoine, Gaël Cobraiville, Lionel Pochet
| ACS Publications
Our previous work established that ACE enables reliable hit validation and quantitative determination of dissociation constants ( KD ) using purified soluble proteins. (7−10) However, extending this approach to membrane proteins presents distinct challenges. These proteins frequently display limited stability in solution and a strong propensity for aggregation due to their hydrophobic domains.
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Adult patients with autoinflammation of unknown origin partially phenocopy the immune presentation of Still’s disease

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By Rafael Plaza Veiga, Leana De Vuyst, Christophe Poulet, Julika Neumann, Leoni Bucken, Teresa Prezzemolo, Mathijs Willemsen, Patrick Matthys, Maximilien Fléron, Dominique Baiwir, Gabriel Mazzucchelli, Bruno Fautrel, Carine Wouters, Dominique de Seny, Stéphanie Humblet-Baron, Adrian Liston, Steven Vanderschueren, Emna Chabaane, Gaël Cobraiville
| Nature Verified
Abstract Autoinflammation of unknown origin remains amongst the most enigmatic of systemic autoinflammatory disorders (SAID), with systemic autoinflammatory symptoms in the absence of a molecular or clinical diagnosis with a recognized SAID. Here, we aim to understand the immunological process behind patients with autoinflammation of unknown origin.
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