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On the Misinterpretation of Fluorescence-Based Quantification in Theranostic Corneal Cross-Linking
To the Editor, We read with great interest the study by Lombardo et al. proposing a theranostic UV-A device for real-time assessment of intracorneal riboflavin concentration during corneal cross-linking (CXL) [1]. While the integration of diagnostic feedback into treatment delivery represents an important technological advance, several fundamental assumptions underlying this approach warrant critical reconsideration.
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