Gaia Barucco
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Effect of Urine Output on the Predictive Precision of NephroCheck in On-Pump Cardiac Surgery With Crystalloid Cardioplegia: Insights from the PrevAKI Study
Highlights • According to the manufacturer, an AKIRisk Score value of ≥0.3 identifies patients at high risk for AKI. • Crystalloid cardioplegia may induce high urine output in the hours after cardiac surgery. • There is a significant inverse relationship between urine output and AKIRisk Score. • AKIRisk Score thresholds may require adjustment for urine output. • Early serum creatinine may be superior to AKIRisk Score in predicting subsequent AKI development.
Effect of Urine Output on the Predictive Precision of NephroCheck in On-Pump Cardiac Surgery with Crystalloid Cardioplegia: Insights from the PrevAKI Study
Object: Previous studies in other settings suggested that urine output (UO) might affect NephroCheck® predictive value. We investigated the correlation between NephroCheck® and UO in cardiac surgery patients. Measurements and Main Results: All patients underwent NephroCheck® testing four hours after CPB discontinuation. The primary outcome was the correlation between urine output, NephroCheck results, and acute kidney injury (AKI - defined according to Kidney Disease: Improving Global Outcome).
JCM | Free Full-Text | Management of Microvascular Bleeding after On-Pump Cardiac Surgery in a Patient with Perioperative Diagnosis of Impairment of Platelet Responses to Adenosine Diphosphate: A Case Report and a Literature Review
1. Introduction Qualitative or quantitative defects of platelet P2Y12 receptor lead to impaired platelet responses to adenosine diphosphate (ADP), a rare condition characterized by a reduced ability of platelets to aggregate and form blood clots in response to ADP stimulation.
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