Gajewski Byron J on Muck Rack

Gajewski Byron J

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Articles

The Evolution of Master Protocol Clinical Trial Designs: A Systematic Literature Review

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By Elias Meyer, Smith Byron, Gajewski Byron J, Byrd John C
| Clinical Therapeutics Verified
Abstract Purpose Recent years have seen a change in the way that clinical trials are being conducted. There has been a rise of designs more flexible than traditional adaptive and group sequential trials which allow the investigation of multiple substudies with possibly different objectives, interventions, and subgroups conducted within an overall trial structure, summarized by the term master protocol.
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