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Ganesan Arunkumar

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Articles

Oncogenic lncRNA transgene transcription modulates epigenetic memory at a naive chromosomal locus.

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By Sweta Sikder, Songjoon Baek, Yamini Dalal, Ganesan Arunkumar
| BioRxiv
Abstract Maintaining genome integrity is crucial for the proper functioning and development of organisms. One intriguing aspect of genome integrity is the formation and function of neocentromeres at non-centromeric sites. CENP-A, a centromere-specific protein, is essential for centromere identification and function. However, in many cancers, CENP-A is often found to be ectopically misplaced when overexpressed.
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