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Gaoying Sun

As seen in: Wiley Online Library
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Articles

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

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By Gaoying Sun, YuKai Wang, Man Wang, Xinyue Wang
| Wiley Online Library Verified
1 Introduction Hearing loss is recognized as the most prevalent sensory disorder globally, with the affected population predicted to reach ≈2 billion by 2050.[1, 2] This consequently imposes a significant socioeconomic burden on both families and society.
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Human Midbrain Organoids Enriched With Dopaminergic Neurons for Long‐Term Functional Evaluation

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By Xinyue Wang, Mingming Tang, Jianhuan Qi, Gaoying Sun
| Wiley Online Library Verified
1 Introduction Dopaminergic (DA) neurons are primarily located in the ventral midbrain, which is involved in the regulation of complex behaviours and locomotion [1-5]. Malfunctioning dopamine neural circuits, such as nigrostriatal and mesolimbic pathways, are central to neurological diseases like Parkinson's disease (PD) [6-9].
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