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Gaozan Zheng

As seen in: Nature, Dialnet - Universidad de La Rioja
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Articles

NDRG2 orchestrates circadian clock stability to suppress tumorigenesis and potentiate oxaliplatin response in colorectal cancer

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By Ruikai Li, Ruxin Ding, Hanjun Dan, Kunli Du, Gaozan Zheng, Siyuan Wang, Lili Duan, Pengfei Wang, Liangliang Shen, Lin Feng, Pan Zhao, Jiajia Wang, Dan Feng, Fengsu Wu, Ziting Zhou, Liaoran Niu, Weidong Wang, Xinyu Qiao, Jianting Yang, Fan Feng, Jianyong Zheng, Jian Zhang, Yumao Yang
| Nature Verified
Abstract Circadian disruption is linked to colorectal cancer (CRC) progression. We investigated the role of the tumor suppressor N-myc downstream-regulated gene 2 (NDRG2) in this context. Intestinal-specific Ndrg2 knockout exacerbated colorectal tumorigenesis in mice under circadian disruption. We identified NDRG2 as a novel stabilizer of the core clock protein Circadian Locomotor Output Cycles Kaput (CLOCK).
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Prognostic value of dynamic changes of pre‑ and post‑operative tumor markers in colorectal cancer

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By Guangming Ren, Gaozan Zheng, Hanjun Dan, Kunli Du
| Dialnet - Universidad de La Rioja
Ayuda Buscar en la ayuda Buscar en la ayuda Prognostic value of dynamic changes of pre‑ and post‑operative tumor markers in colorectal cancer Guangming Ren [1] ; Gaozan Zheng [1] ; Kunli Du [1] ; Hanjun Dan [1] ; Xinyu Dou [1] ; Lili Duan [1] ; Zhenyu Xie [1] ; Liaoran Niu [1] ; Ye Tian [1] ; Jianyong Zheng [1] ; Fan Feng [1] ; Zhangfeng Dang [2] [1] Department of Gastrointestinal Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an, China [2] Department of General Surgery, Air...
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Clinicopathological features and prognosis of gastric adenosquamous carcinoma

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By Qiao Wang, Gaozan Zheng, Jingpeng Qi, Guanghui Xu
| Nature Verified
Gastric ASC is an extremely rare entity and account for less than 1% of all gastric malignancies1. Thus, the clinicopathological features and prognosis of gastric ASC was unclear. In the present study, we found that gastric ASC differ significantly from gastric AC with respect to clinicopathological features, and the prognosis of gastric ASC was worse than that of gastric AC. Up to date, there was only one study containing a relatively large number of gastric ASC patients3.
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