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Garcia Bardales on Muck Rack

Garcia Bardales

As seen in: Oxford Academic
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Articles

Defining severe shigellosis in the Enterics for Global Health study: A comparison of leading diarrhea severity definitions among children with Shigella diarrhea

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By Olivia Lang, M Jahangir, Asociacion Benefica PRISMA, Garcia Bardales
| Oxford Academic Verified
Shigella has high global burden and serious long-term outcomes among young children. Increasing antibiotic resistance makes Shigella vaccine development a critical priority. Choosing the optimal clinical efficacy endpoint for Shigella vaccine trials requires comparing existing diarrhea severity definitions among children with Shigella. Six- to 35-month-old children presenting to a clinic with diarrhea were enrolled in Bangladesh, Kenya, Malawi, Mali, Pakistan, Peru, and The Gambia.
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